Papers by Ye Ouyang

7 papers
Biology-Instructions: A Dataset and Benchmark for Multi-Omics Sequence Understanding Capability of Large Language Models (2025.findings-emnlp)

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Challenge: Biology-Instructions is the first large-scale instruction-tuning dataset for multi-omics biological sequences.
Approach: They propose a large-scale instruction-tuning dataset for multi-omics biological sequences . they propose 'chatMultiOmics' to overcome limitations of current LLMs on multi-ome tasks .
Outcome: The proposed dataset bridges LLMs and complex biological sequence-related tasks while maintaining conversational fluency.
Nature-Inspired Population-Based Evolution of Large Language Models (2026.acl-long)

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Challenge: a new framework for population-based evolution of large language models is emerging . a population-driven evolution of LLMs is a key component of evolution, authors say .
Approach: They propose a framework that allows for population-based evolution of large language models . they start with a population of parent LLMs and allow this population to evolve .
Outcome: The proposed framework outperforms existing methods on 12 datasets.
SwapMoE: Serving Off-the-shelf MoE-based Large Language Models with Tunable Memory Budget (2024.acl-long)

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Challenge: Mixture of experts (MoE) is a popular technique to improve capacity of Large Language Models (LLMs) but memory-constrained devices are a major concern in edge AI training and serving.
Approach: They propose a framework for efficient serving of MoE-based large language models with tunable memory budgets.
Outcome: Experiments show that SwapMoE can reduce memory consumption while maintaining reasonable accuracy.
What Makes LLMs Effective Sequential Recommenders? A Study on Preference Intensity and Temporal Context (2026.acl-long)

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Challenge: Existing preference-alignment approaches rely on binary pairwise comparisons, overlooking preference intensity and temporal context.
Approach: They propose a unified preference optimization framework that maps both explicit and implicit feedback into a common preference signal and constructs adaptive reward margins that jointly account for preference intensity and interaction recency.
Outcome: The proposed framework outperforms state-of-the-art recommendations while maintaining behavioral patterns aligned with human decision-making.
A Scalable Multi-LLM Collaboration System with Retrieval-based Selection and Exploration-Exploitation-Driven Enhancement (2026.acl-long)

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Challenge: Existing multi-LLM collaboration systems often encounter scalability challenges when integrating new LLMs and tasks.
Approach: They propose a Scalable Multi-LLM Collaboration System to coordinate multiple open-source LLMs.
Outcome: The proposed system outperforms prevailing closed-source LLMs on eight mainstream benchmarks on multiple tasks.
WACO: Word-Aligned Contrastive Learning for Speech Translation (2023.acl-long)

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Challenge: Existing ST methods perform poorly when only a limited amount of parallel data are available for training.
Approach: They propose a Word-Aligned COntrastive learning method for low-resource speech-to-text translation that bridges word-level representations for both speech and text modalities via contrastive learning.
Outcome: The proposed method outperforms the best baseline by 9+ BLEU points with only 1-hour parallel ST data.
Energy-based Unknown Intent Detection with Data Manipulation (2021.findings-acl)

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Challenge: Unknown intent detection aims to identify the out-of-distribution (OOD) utterance whose intent has never appeared in the training set.
Approach: They propose a framework to generate high-quality OOD utterances with importance weighTs (GOT) their framework is fine-tuned to detect out-of-distribution utterrances .
Outcome: The proposed framework can achieve state-of-the-art results on two benchmark datasets.

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