Papers by Wanli Ouyang
Dolphin: Moving Towards Closed-loop Auto-research through Thinking, Practice, and Feedback (2025.acl-long)
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Jiakang Yuan, Xiangchao Yan, Bo Zhang, Tao Chen, Botian Shi, Wanli Ouyang, Yu Qiao, Lei Bai, Bowen Zhou
| Challenge: | Recent studies show that AI-assisted research methods can improve research efficiency . a closed-loop framework is used to enhance the automation level of scientific research . |
| Approach: | They propose a closed-loop LLM-driven framework to enhance the automation level of scientific research. |
| Outcome: | The proposed framework improves the efficiency of scientific research by improving data analysis, accelerating computation, and fostering novel idea generation. |
Biology-Instructions: A Dataset and Benchmark for Multi-Omics Sequence Understanding Capability of Large Language Models (2025.findings-emnlp)
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Haonan He, Yuchen Ren, Yining Tang, Ziyang Xu, Junxian Li, Minghao Yang, Di Zhang, Yuan Dong, Tao Chen, Shufei Zhang, Yuqiang Li, Nanqing Dong, Wanli Ouyang, Dongzhan Zhou, Peng Ye
| Challenge: | Biology-Instructions is the first large-scale instruction-tuning dataset for multi-omics biological sequences. |
| Approach: | They propose a large-scale instruction-tuning dataset for multi-omics biological sequences . they propose 'chatMultiOmics' to overcome limitations of current LLMs on multi-ome tasks . |
| Outcome: | The proposed dataset bridges LLMs and complex biological sequence-related tasks while maintaining conversational fluency. |
VocabTailor: Dynamic Vocabulary Selection for Downstream Tasks in Small Language Models (2026.findings-acl)
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| Challenge: | Existing static vocabulary pruning designs that reduce memory usage suffer from rigid, one-size-fits-all designs that cause information loss during the prefill stage and lack flexibility. |
| Approach: | They propose a decoupled dynamic vocabulary selection framework that addresses memory constraints through offloading embedding and implements a hybrid static-dynamic vocabulary selection strategy for LM Head. |
| Outcome: | The proposed framework reduces memory usage by 99% with minimal or no degradation in performance. |
Many Heads Are Better Than One: Improved Scientific Idea Generation by A LLM-Based Multi-Agent System (2025.acl-long)
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Haoyang Su, Renqi Chen, Shixiang Tang, Zhenfei Yin, Xinzhe Zheng, Jinzhe Li, Biqing Qi, Qi Wu, Hui Li, Wanli Ouyang, Philip Torr, Bowen Zhou, Nanqing Dong
| Challenge: | Recent AI methods have shown promise in tasks such as hypothesis generation and experimental design, but they fail to replicate the collaborative nature of real-world scientific practices. |
| Approach: | They propose a virtual scientific system that mimics the collaborative nature of scientific research by organizing a team of agents to generate, evaluate, and refine research ideas. |
| Outcome: | The proposed system outperforms the state-of-the-art method in producing new scientific ideas and offers valuable insights to guide future research. |
ResearchBench: Benchmarking LLMs in Scientific Discovery via Inspiration-Based Task Decomposition (2026.findings-acl)
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Yujie Liu, Zonglin Yang, Tong Xie, Jinjie Ni, Ben Gao, Yuqiang Li, Shixiang Tang, Wanli Ouyang, Erik Cambria, Dongzhan Zhou
| Challenge: | Large language models have shown potential in assisting scientific research, yet their ability to discover high-quality research hypotheses remains unexamined due to the lack of a dedicated benchmark. |
| Approach: | They propose a benchmark for evaluating large language models on a sufficient set of scientific discovery sub-tasks. |
| Outcome: | The proposed framework extracts critical components from papers across 12 disciplines with expert validation confirming its accuracy. |
Beyond One-Preference-Fits-All Alignment: Multi-Objective Direct Preference Optimization (2024.findings-acl)
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| Challenge: | Recent approaches to language model alignment assume homogeneous human preferences, but actual human preferences vary widely and are hard to satisfy with a single language model. |
| Approach: | They propose an RL-free extension of Direct Preference Optimization (DPO) that folds language modeling directly into reward modeling and trains language models as collective reward models that combine all objectives with specific weights. |
| Outcome: | The proposed method matches or outperforms existing methods in safety alignment and long-form question answering. |
Nature-Inspired Population-Based Evolution of Large Language Models (2026.acl-long)
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| Challenge: | a new framework for population-based evolution of large language models is emerging . a population-driven evolution of LLMs is a key component of evolution, authors say . |
| Approach: | They propose a framework that allows for population-based evolution of large language models . they start with a population of parent LLMs and allow this population to evolve . |
| Outcome: | The proposed framework outperforms existing methods on 12 datasets. |
ROGRAG: A Robustly Optimized GraphRAG Framework (2025.acl-demo)
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| Challenge: | Existing pipelines for large language models struggle with specialized or emerging topics which are rarely seen in the training corpus. |
| Approach: | They propose a multi-stage retrieval mechanism that integrates dual-level with logic form retrieval methods to improve retrieval robustness without increasing computational cost. |
| Outcome: | The proposed framework outperforms Qwen2.5-7B-Instruct and outperformed mainstream methods on seedbench and significantly improves the performance of each component. |
LOCR: Location-Guided Transformer for Optical Character Recognition (2024.findings-emnlp)
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| Challenge: | Academic documents are packed with texts, equations, tables, and figures, posing challenges for accurate OCR results. |
| Approach: | They propose a model that integrates location guiding into the transformer architecture during autoregression. |
| Outcome: | The proposed model outperforms existing methods on an original large-scale dataset comprising 53M text-location pairs from 89K academic document pages. |
RoleLLM: Benchmarking, Eliciting, and Enhancing Role-Playing Abilities of Large Language Models (2024.findings-acl)
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Noah Wang, Z.y. Peng, Haoran Que, Jiaheng Liu, Wangchunshu Zhou, Yuhan Wu, Hongcheng Guo, Ruitong Gan, Zehao Ni, Jian Yang, Man Zhang, Zhaoxiang Zhang, Wanli Ouyang, Ke Xu, Wenhao Huang, Jie Fu, Junran Peng
| Challenge: | Large Language Models (LLMs) have paved the way for complex tasks such as role-playing. |
| Approach: | They propose a framework to benchmark, elicit, and enhance role-playing abilities in Large Language Models. |
| Outcome: | The proposed framework improves role-playing abilities with 168,093 samples. |
LLaMA-Berry: Pairwise Optimization for Olympiad-level Mathematical Reasoning via O1-like Monte Carlo Tree Search (2025.naacl-long)
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Di Zhang, Jianbo Wu, Jingdi Lei, Tong Che, Jiatong Li, Tong Xie, Xiaoshui Huang, Shufei Zhang, Marco Pavone, Yuqiang Li, Wanli Ouyang, Dongzhan Zhou
| Challenge: | LLaMA-Berry is an advanced mathematical reasoning framework to enhance the problem-solving ability of large language models (LLMs). |
| Approach: | They propose a Monte Carlo Tree Search and Self-Refine framework to optimize reasoning paths and a pairwise reward model to evaluate different paths globally. |
| Outcome: | The proposed framework overcomes inefficiencies and limitations of step-wise and greedy search algorithms, enabling more efficient exploration of solution spaces. |
A Scalable Multi-LLM Collaboration System with Retrieval-based Selection and Exploration-Exploitation-Driven Enhancement (2026.acl-long)
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Shengji Tang, Jianjian Cao, Weihao Lin, Jiale Hong, Bo Zhang, Shuyue Hu, Lei Bai, Tao Chen, Wanli Ouyang, Peng Ye
| Challenge: | Existing multi-LLM collaboration systems often encounter scalability challenges when integrating new LLMs and tasks. |
| Approach: | They propose a Scalable Multi-LLM Collaboration System to coordinate multiple open-source LLMs. |
| Outcome: | The proposed system outperforms prevailing closed-source LLMs on eight mainstream benchmarks on multiple tasks. |
ConceptMath: A Bilingual Concept-wise Benchmark for Measuring Mathematical Reasoning of Large Language Models (2024.findings-acl)
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Yanan Wu, Jie Liu, Xingyuan Bu, Jiaheng Liu, Zhanhui Zhou, Yuanxing Zhang, Chenchen Zhang, ZhiqiBai ZhiqiBai, Haibin Chen, Tiezheng Ge, Wanli Ouyang, Wenbo Su, Bo Zheng
| Challenge: | ConceptMath evaluates concept-wise mathematical reasoning of Large Language Models (LLMs) Existing benchmarks that evaluate general mathematical reasoning with an average accuracy fail to probe the fine-grained failure modes of mathematical reasoning on specific datasets. |
| Approach: | They introduce a bilingual, fine-grained benchmark that evaluates concept-wise mathematical reasoning of Large Language Models. |
| Outcome: | The proposed benchmarks evaluate concept-wise mathematical reasoning of Large Language Models with concept-based accuracies. |
MT-Bench-101: A Fine-Grained Benchmark for Evaluating Large Language Models in Multi-Turn Dialogues (2024.acl-long)
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Ge Bai, Jie Liu, Xingyuan Bu, Yancheng He, Jiaheng Liu, Zhanhui Zhou, Zhuoran Lin, Wenbo Su, Tiezheng Ge, Bo Zheng, Wanli Ouyang
| Challenge: | Large Language Models (LLMs) have greatly enhanced dialogue systems, but evaluation of their capabilities remains a challenge. |
| Approach: | They propose a model to evaluate the fine-grained abilities of Large Language Models in multi-turn dialogues. |
| Outcome: | The proposed model evaluates 21 popular chatbots based on MT-Bench-101 . it includes 3 overarching abilities and 13 distinct tasks within multi-turn dialogue scenarios. |
GraphReader: Building Graph-based Agent to Enhance Long-Context Abilities of Large Language Models (2024.findings-emnlp)
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Shilong Li, Yancheng He, Hangyu Guo, Xingyuan Bu, Ge Bai, Jie Liu, Jiaheng Liu, Xingwei Qu, Yangguang Li, Wanli Ouyang, Wenbo Su, Bo Zheng
| Challenge: | Existing models for long contexts struggle to handle long inputs due to limited context window and memory usage. |
| Approach: | They propose a graph-based agent system that analyzes long texts into a graphical graph . GraphReader consistently outperforms GPT-4-128k across context lengths from 16k to 256k . |
| Outcome: | The proposed model outperforms existing models on four challenging benchmarks. |