Challenge: Existing approaches to biomedical relation extraction (RE) are limited due to the scarcity of annotations and the prevalence of instances without explicitly pre-defined labels.
Approach: They propose a method which converts biomedical relation extraction (RE) as natural language inference formulation through indirect supervision.
Outcome: Extensive experiments on three widely-used biomedical RE benchmarks show that indirect supervision improves biomedically relation extraction even when a domain gap exists.

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Challenge: Existing methods for extracting structured data from unstructured texts neglect unique features of the biomedical literature, such as ambiguous entities and nested proper nouns.
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Challenge: Existing methods for relation extraction are limited to costly hand-labeled training sets and hard to be extended to large-scale relations.
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Deep Bidirectional Transformers for Relation Extraction without Supervision (D19-61)

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Challenge: Existing frameworks for relation extraction use distant supervision instead of annotated data.
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MedDistant19: Towards an Accurate Benchmark for Broad-Coverage Biomedical Relation Extraction (2022.coling-1)

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Challenge: Relation extraction in the biomedical domain is challenging due to the lack of labeled data and high annotation costs.
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Challenge: Recent research has explored the potential of leveraging natural language inference (NLI) techniques to enhance relation extraction (RE).
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Challenge: Existing methods to extract textual relations with distant supervision are limited by their reliance on supervised training data.
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Indirectly Supervised Natural Language Processing (2023.acl-tutorials)

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Challenge: a tutorial on indirect supervision addresses challenges in ML for NLP . conventional approaches to NLP use taskspecific labeled examples of a large volume . indirect supervision is useful for a wide range of NLP tasks, but it is not enough for decoders .
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Revisiting Distant Supervision for Relation Extraction (L18-1)

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Challenge: Existing approaches for relation extraction (RE) use supervised learning on relation-specific training data, which is expensive to acquire.
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Challenge: Discourse relation classification is a challenging task when the text domain is different from the standard Penn Discourse Treebank (PDTB) training corpus domain.
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BioNLI: Generating a Biomedical NLI Dataset Using Lexico-semantic Constraints for Adversarial Examples (2022.findings-emnlp)

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Challenge: Biomedical research has progressed at a tremendous pace, with PubMed2 indexing well over 1M publications per year in the past eight years.
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