Papers with diagnosis

23 papers
Task-oriented Dialogue System for Automatic Diagnosis (P18-2)

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Challenge: Existing methods to identify phenotypes using electronic health records (EHRs) are expensive and difficult to transfer models from one disease to another.
Approach: They propose a task-oriented dialogue system framework to make diagnosis for patients automatically, which can converse with patients to collect additional symptoms beyond their self-reports.
Outcome: The proposed system can collect additional symptoms from conversation and improve disease identification accuracy.
MedDecXtract: A Clinician-Support System for Extracting, Visualizing, and Annotating Medical Decisions in Clinical Narratives (2025.acl-demo)

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Challenge: Clinical notes contain important information about medical decisions embedded within unstructured text.
Approach: They propose an open-source interactive system that automatically extracts medical decisions from clinical text.
Outcome: The open-source system extracts and visualizes medical decisions from clinical text.
To What Extent Do Natural Language Understanding Datasets Correlate to Logical Reasoning? A Method for Diagnosing Logical Reasoning. (2022.coling-1)

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Challenge: Reasoning and knowledge-related skills are considered as fundamental skills for natural language understanding (NLU) tasks.
Approach: They propose a method to diagnose correlations between an NLU dataset and a specific skill.
Outcome: The proposed method is able to diagnose correlations between dataset and logical reasoning skill on 8 MRC and 3 NLI datasets.
Counterfactual Supporting Facts Extraction for Explainable Medical Record Based Diagnosis with Graph Network (2021.naacl-main)

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Challenge: Existing methods provide explanations based on a precise medical knowledge base, which is disease-specific and difficult to obtain for experts in reality.
Approach: They propose a method to extract supporting facts from irregular EMR without external knowledge bases by constructing a hierarchical graph network and using it to obtain causal relationship between multi-granularity features and diagnosis results.
Outcome: The proposed method diagnoses four types of EMR correctly and provides accurate supporting facts for the results.
D4: a Chinese Dialogue Dataset for Depression-Diagnosis-Oriented Chat (2022.emnlp-main)

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Challenge: Existing human-machine dialogue systems are not able to provide diagnostic information for depression diagnosis due to stigma associated with mental illness.
Approach: They propose to construct a Chinese Dialogue Dataset for depression-diagnosis-oriented chat based on clinical depression diagnostic criteria.
Outcome: The proposed system can be used to diagnose depression using a Chinese Dialogue Dataset.
Language and Mental Health: Measures of Emotion Dynamics from Text as Linguistic Biosocial Markers (2023.emnlp-main)

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Challenge: valence variability was significantly lower in the control group compared to ADHD, depression, bipolar disorder, MDD, PTSD, and OCD but not PPD.
Approach: They study the relationship between tweet emotion dynamics and mental health disorders by using a user-disclosed diagnosis.
Outcome: The results show that the measures varied by the user's self-disclosed diagnosis.
On the Automatic Generation of Medical Imaging Reports (P18-1)

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Challenge: a complete medical imaging report contains multiple heterogeneous forms of information, including findings and tags . abnormal regions in medical images are difficult to identify and the reports are typically long, containing multiple sentences.
Approach: They propose a multi-task learning framework which predicts tags and generates paragraphs for abnormal regions in medical images.
Outcome: The proposed framework can generate long paragraphs on two publicly available datasets.
Towards Reducing Diagnostic Errors with Interpretable Risk Prediction (2024.naacl-long)

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Challenge: Diagnostic errors occur because clinicians cannot easily access relevant information in EHRs.
Approach: They propose a method to use LLMs to identify pieces of evidence that indicate increased or decreased risk of specific diagnoses in patient EHRs.
Outcome: The proposed method reduces diagnostic errors by identifying evidence in patient EHRs . it uses a Neural Additive Model to make predictions backed by evidence at time-points where clinicians are uncertain .
MidMed: Towards Mixed-Type Dialogues for Medical Consultation (2023.acl-long)

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Challenge: Current medical dialogue systems assume that patients have explicit goals but are often unavailable in real-world situations due to the lack of medical knowledge.
Approach: They propose a human-to-human mixed-type medical consultation dialogue corpus . they build benchmarking baselines on MidMed and propose an instruction-guiding framework . Experimental results show the effectiveness of InsMed .
Outcome: The proposed system can help patients clarify their goals in real-world situations . it covers four departments with 8,309 dialogues and provides benchmarking baselines .
The Tembusu Treebank: An English Learner Treebank (2022.lrec-1)

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Challenge: a new treebank is created to help diagnose ungrammatical sentences using mal-rules . the Tembusu Learner Treebank is an open treebank created from the corpus of Learner English .
Approach: They propose to use the Tembusu Learner Treebank to train a new parse-ranking model for the English Resource Grammar . the model incorporates mal-rules in the annotation of ungrammatical sentences .
Outcome: The Tembusu Learner Treebank is an open treebank created from the NTU Corpus of Learner English . the treebank is unique for incorporating mal-rules in the annotation of ungrammatical sentences .
Zero-Shot Entailment Learning for Ontology-Based Biomedical Annotation Without Explicit Mentions (2025.coling-main)

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Challenge: Automated biomedical annotation presents significant challenges when entities are not explicitly mentioned in the text.
Approach: They propose an entailment-based zero-shot text classification approach to annotate biomedical text passages using the Homeostasis Imbalance Process (HOIP) ontology.
Outcome: The proposed method performs well when processes are not explicitly mentioned . it is time-consuming and expensive to annotate biomedical texts with a specific ontology .
VPL: Visual Proxy Learning Framework for Zero-Shot Medical Image Diagnosis (2024.findings-emnlp)

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Challenge: Insufficient medical text precision and the modal disparity between text and vision spaces pose challenges for vision-language models like CLIP.
Approach: They propose a visual proxy learning framework that combines a text refinement module and a stable Sinkhorn algorithm to enhance the diagnostic performance.
Outcome: The proposed model outperforms the state-of-the-art CLIP inference by 1.69% to 15.31% on five datasets covering various diseases.
Exploring Compositional Generalization of Multimodal LLMs for Medical Imaging (2025.acl-long)

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Challenge: Current research suggests that multitask training outperforms single-task as different tasks can benefit each other, but they often overlook the internal relationships within these tasks.
Approach: They employ compositional generalization (CG) to examine the generalization of multimodal large language models in medical imaging.
Outcome: The proposed model can understand unseen medical images and is able to perform CG across classification and detection tasks.
MedEx: Enhancing Medical Question-Answering with First-Order Logic based Reasoning and Knowledge Injection (2025.coling-main)

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Challenge: Existing knowledge triples are ineffective in medical question-answering because of superfluous data and inability to capture complex relationships between symptoms and treatments.
Approach: They propose a first-order logical reasoning model that uses First-Order Logic to model intricate relationships between diseases and treatments.
Outcome: The proposed model captures the interplay of symptoms, diseases, and treatments, enhancing context comprehension.
Seeing the Whole Elephant: A Benchmark for Failure Attribution in LLM-based Multi-Agent Systems (2026.acl-long)

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Challenge: Existing benchmarks rely on partially observable traces that capture only agent outputs . lack of full execution traces obscures many failure causes, authors argue .
Approach: They propose a benchmark that allows attribution under full execution observability . they find full traces improve attribution accuracy by up to 76.5% over a partial-observation counterpart .
Outcome: The proposed benchmark improves attribution accuracy by up to 76.5% over a partial-observation counterpart.
MediTOD: An English Dialogue Dataset for Medical History Taking with Comprehensive Annotations (2024.emnlp-main)

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Challenge: Existing datasets lacking comprehensive annotations for medical history-taking are non-English . existing datasets lack comprehensive annotation for medical slots and their attributes .
Approach: They propose a dataset of doctor-patient dialogues in English for medical history-taking task.
Outcome: The proposed datasets are available in English and are compared with existing datasets.
ClinicalMC: A Benchmark for Multi-Course Clinical Decision-Making with Large Language Models (2026.findings-acl)

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Challenge: Existing benchmarks assess LLM performance in single-course settings and lack systematic evaluation in multi-course scenarios, where a patient’s condition evolves over time.
Approach: They propose to use large language models to assess their performance in multi-course clinical decision-making scenarios where a patient’s condition evolves over time.
Outcome: The proposed model includes 1,275 Chinese and 5,804 English samples across four stages from admission to discharge.
MKeCL: Medical Knowledge-Enhanced Contrastive Learning for Few-shot Disease Diagnosis (2024.lrec-main)

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Challenge: Existing approaches to disease classification are limited in real-world clinics due to insufficient data and inflexibility.
Approach: They propose a medical knowledge-Enhanced Contrastive Learning approach to disease diagnosis . they incorporate medical knowledge graphs and medical licensing exams in modeling .
Outcome: The proposed model outperforms existing models on real clinical EMRs on a single patient.
Semantic Similarity Models for Depression Severity Estimation (2023.emnlp-main)

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Challenge: Public health systems have limited capacity for case detection and diagnosis due to the widespread use of social media.
Approach: They propose to use social media content to generate semantic rankings for depressive symptoms and severity levels and use them to predict symptoms severity.
Outcome: The proposed pipeline improves on two Reddit-based benchmarks and shows that it is more efficient than state-of-the-art in terms of measuring depression level.
AMANDA: Agentic Medical Knowledge Augmentation for Data-Efficient Medical Visual Question Answering (2025.findings-emnlp)

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Challenge: Existing Med-MLLMs fail when deployed in low-resource settings where abundant labeled data is unavailable.
Approach: They propose a training-free agentic framework that performs medical knowledge augmentation via LLM agents.
Outcome: The proposed framework performs medical knowledge augmentation via LLM agents.
MedEinst: Benchmarking the Einstellung Effect in Medical LLMs through Counterfactual Differential Diagnosis (2026.acl-long)

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Challenge: Existing medical benchmarks fail to detect the Einstellung Effect in clinical diagnosis . Existing models exhibit the Einstellung effect, relying on statistical shortcuts rather than logical reasoning.
Approach: They propose a counterfactual benchmark that uses statistical shortcuts to diagnose patients . they propose CGME-based system that iteratively refines reasoning paths .
Outcome: The proposed model achieves high baseline accuracy but severe bias trap rates . iteratively refines reasoning paths in an exemplar base and consolidates disease-specific knowledge into illness graphs.
ROSCO-Omni: Multimodal LLM-Based Communication Understanding for Non- and Minimally-Speaking Autistic Individuals (2026.findings-acl)

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Challenge: 30% of autistic individuals remain non- or minimally-speaking throughout their lives . however, caregivers rely on simultaneous integration of visual cues, auditory signals, and contextual understanding to infer intent.
Approach: They propose a framework that fine tunes a teacher-student MLLM for domain-specialized inference.
Outcome: The proposed framework achieves comparable performance to closed-source models .
LLM-Based Multi-Agent Systems for Clinical Workflows: A Survey of AI Hospitals (2026.acl-long)

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Challenge: Large Language Models (LLMs) are moving from isolated text generation toward agentic work inside clinical workflows.
Approach: They propose a workflow-level taxonomy for LLM-based multi-agent systems for clinical and healthcare workflows . they propose integration readiness levels, task-level instrumentation requirements and recurring workflow failure modes as a practical framework for comparing, evaluating and deploying clinical LLM agents and AI hospitals.
Outcome: The proposed systems should be compared at the workflow level, rather than only by model components or end-task accuracy.

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