Challenge: Existing medical LLMs focus primarily on diagnosis recommendation, limiting their clinical applicability.
Approach: They propose a medical LLM that integrates heterogeneous EHR data into clinically grounded dialogues.
Outcome: The proposed model outperforms baselines in clinical test recommendation and diagnosis prediction.

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Interactive Evaluation for Medical LLMs via Task-oriented Dialogue System (2025.coling-main)

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Challenge: In typical medical scenarios, doctors often ask a set of questions to gain a comprehensive understanding of patients’ conditions.
Approach: They propose to use multi-turn medical dialogue evaluation to evaluate proactive communication and diagnostic capabilities of medical Large Language Models (LLMs) .
Outcome: The proposed model outperforms existing models on multi-turn question-answering datasets and is therefore cost-effective.
DialMed: A Dataset for Dialogue-based Medication Recommendation (2022.coling-1)

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Challenge: Existing studies on medication recommendation mainly rely on EHRs, but some details of interactions between doctors and patients may be ignored or omitted in EHR.
Approach: They propose to use medical dialogues to recommend medications with medical dialogue data . they propose to model dialogue structure and disease knowledge aware network .
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CARER - ClinicAl Reasoning-Enhanced Representation for Temporal Health Risk Prediction (2024.emnlp-main)

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Challenge: Existing deep learning methods require large datasets to achieve high generalizability.
Approach: They propose a framework that enhances deep learning models with clinical rationales derived from medically proficient Large Language Models.
Outcome: The proposed framework outperforms state-of-the-art models on two tasks using two popular EHR datasets by up to 11.2%.
Task-oriented Dialogue System for Automatic Diagnosis (P18-2)

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Challenge: Existing methods to identify phenotypes using electronic health records (EHRs) are expensive and difficult to transfer models from one disease to another.
Approach: They propose a task-oriented dialogue system framework to make diagnosis for patients automatically, which can converse with patients to collect additional symptoms beyond their self-reports.
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RePrompT: Recurrent Prompt Tuning for Integrating Structured EHR Encoders with Large Language Models (2026.findings-acl)

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Challenge: Large Language Models (LLMs) have shown promising results for mining EHRs . translating time-stamped sequences into plain text can obscure both temporal structure and code identities, weakening the ability to capture code co-occurrence and longitudinal regularities.
Approach: They propose a time-aware LLM framework that integrates structured EHR encoders through prompt tuning without modifying underlying architectures.
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PromptEHR: Conditional Electronic Healthcare Records Generation with Prompt Learning (2022.emnlp-main)

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Challenge: Existing methods for generating longitudinal multimodal EHRs are limited due to privacy concerns.
Approach: They propose to generate longitudinal multimodal EHRs by unconditional generation or longitudinal inference . existing methods generate single-modal E HRs by conditional generation or by longitudinal inferment .
Outcome: The proposed method is more flexible and controllable than existing methods and is more cost-effective than existing ones.
Large Language Models with Temporal Reasoning for Longitudinal Clinical Summarization and Prediction (2025.findings-emnlp)

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Challenge: Recent advances in large language models have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored.
Approach: They evaluate open-source large language models, their Retrieval Augmented Generation variants and chain-of-thought prompting on long-context clinical summarization and prediction.
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The AI Doctor Is In: A Survey of Task-Oriented Dialogue Systems for Healthcare Applications (2022.acl-long)

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Challenge: Task-oriented dialogue systems have been surveyed in the medical community from a non-technical perspective, but a systematic review from . a rigorous computational perspective has to date remained noticeably absent.
Approach: They analyze 4070 papers on task-oriented dialogue systems for healthcare applications and identify gaps in their analysis.
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EMSDialog: Synthetic Multi-person Emergency Medical Service Dialogue Generation from Electronic Patient Care Reports via Multi-LLM Agents (2026.findings-acl)

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Challenge: Existing medical dialogue corpora are largely dyadic or lack multi-party workflow and annotations needed for this setting.
Approach: They propose an ePCR-grounded, topic-flow-based multi-agent generation pipeline that iteratively plans, generates, and self-refines dialogues with rule-based factual and topic flow checks.
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RAM-EHR: Retrieval Augmentation Meets Clinical Predictions on Electronic Health Records (2024.acl-short)

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Challenge: Existing deep learning models for EHRs rely on knowledge from a single source and do not capture the semantic information for medical codes.
Approach: They propose a Retrieval AugMentation pipeline to augment clinical prediction on EHRs . they use multiple knowledge sources to convert them into text and use consistency regularization to capture complementary information from patient visits and summarized knowledge.
Outcome: Experiments on two EHR datasets show that RAM-EHR improves clinical prediction tasks.

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