Challenge: Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions.
Approach: They propose to investigate the use of Natural Language Processing (NLP) techniques to identify, appraise, synthesize, apply, and disseminate evidence in EBM.
Outcome: The proposed methods support the five fundamental steps of EBM—Ask, Acquire, Appraise, Apply, and Assess.

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Applications of Natural Language Processing in Clinical Research and Practice (N19-5)

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Challenge: a tutorial on clinical NLP will introduce students and experts to the field . a focus will be on the use of clinical Nlp in clinical research and practice .
Approach: This tutorial introduces the clinical use of natural language processing (NLP) techniques . it will review techniques and tools developed for the clinical domain .
Outcome: This tutorial will introduce the clinical NLP methodologies and tools at two top universities . the goal of the tutorial is to encourage NLP researchers in the general domain to contribute .
NLI4CT: Multi-Evidence Natural Language Inference for Clinical Trial Reports (2023.emnlp-main)

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Challenge: Clinical trial reports (CTRs) are indispensable for the development of personalized medicine.
Approach: They propose a resource to help researchers interpret clinical trial reports . they use natural language inference to compute textual entailment .
Outcome: The proposed resource is the first to cover interpretation of full clinical trial reports . it includes tasks to determine inference relation between natural language statements and CTRs .
Inferring Which Medical Treatments Work from Reports of Clinical Trials (N19-1)

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Challenge: Ideally, one would consult all available evidence from relevant clinical trials. however, these results are primarily disseminated in natural language scientific articles.
Approach: They propose a task that involves inferring results from a full-text article describing randomized controlled trials with respect to a given intervention, comparator, and outcome of interest.
Outcome: The proposed task consists of 10,000+ prompts coupled with full-text articles describing randomized controlled trials.
A Corpus with Multi-Level Annotations of Patients, Interventions and Outcomes to Support Language Processing for Medical Literature (P18-1)

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Challenge: In 2015 alone, about 100 manuscripts describing randomized controlled trials for medical interventions were published every day.
Approach: They propose a corpus of 5,000 medical articles annotated with demarcations of text spans that describe the Patient population enrolled, the Interventions studied and to what they were Compared, and the Outcomes measured.
Outcome: The proposed corpus includes 5,000 medical articles describing clinical randomized controlled trials.
Incorporating medical knowledge in BERT for clinical relation extraction (2021.emnlp-main)

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Challenge: Pre-trained language models (PLMs) are used for diverse NLP tasks such as Information Extraction, Sentiment Analysis and Question/Answering.
Approach: They propose to add medical knowledge to pre-trained language models to facilitate clinical relation extraction using a large text corpus.
Outcome: The proposed model outperforms the state-of-the-art systems on the benchmark i2b2/VA 2010 clinical relation extraction dataset.
Knowledge-Augmented Methods for Natural Language Processing (2022.acl-tutorials)

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Challenge: Knowledge in natural language processing (NLP) is a rising trend especially after the advent of large scale pre-trained models.
Approach: This tutorial introduces the key steps in integrating knowledge into natural language processing (NLP) it introduces knowledge grounding from text, knowledge representation and fusing.
Outcome: This tutorial introduces the key steps in integrating knowledge into natural language processing including knowledge grounding from text, knowledge representation and fusing.
imapScore: Medical Fact Evaluation Made Easy (2024.findings-acl)

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Challenge: Automated evaluation of natural language generation tasks fails to focus on medical QA because of the diversity in medical terminology.
Approach: They propose a new data structure, imap, to capture key information in questions and answers.
Outcome: The proposed model outperforms state-of-the-art metrics in correlation with human scores.
Appraising the Potential Uses and Harms of LLMs for Medical Systematic Reviews (2023.emnlp-main)

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Challenge: Medical systematic reviews are time-consuming and often generate inaccurate outputs . authors: a model that generates scientific-sounding outputs can be unusable at best .
Approach: They conduct interviews with systematic review experts to characterize perceived utility and risks of LLMs in medical evidence reviews.
Outcome: a new study characterizes perceived utility and risks of medical evidence reviews . experts say they can assist in the writing process by drafting summaries, distilling information . authors say they expect the model to be more accurate and more reliable .
Natural Language Processing for Human Resources: A Survey (2025.naacl-industry)

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Challenge: Recent advances in NLP have the potential to transform HR processes, from recruitment to employee management.
Approach: They analyze key tasks such as information extraction and text classification and their roles in downstream applications like recommendation and language generation while discussing ethical concerns.
Outcome: The proposed frameworks can be applied to HR tasks and to recommendation, language generation, and interaction.
Towards Comprehensive Language Analysis for Clinically Enriched Spontaneous Dialogue (2024.lrec-main)

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Challenge: Contemporary NLP has progressed from feature-based classification to fine-tuning and prompt-based techniques . many of these techniques remain understudied in the context of real-world, clinically enriched spontaneous dialogue.
Approach: They investigate the efficacy and overall performance of a range of NLP techniques on transcribed speech from patients with schizophrenia and other disorders.
Outcome: The proposed methods are effective in analyzing transcribed speech from patients with schizophrenia and healthy controls taking a clinically-validated language test.

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