Papers by Iain Marshall

8 papers
Automatically Summarizing Evidence from Clinical Trials: A Prototype Highlighting Current Challenges (2023.eacl-demo)

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Challenge: Existing systems that retrieve trial publications matching a query are inefficient and introduce unsupported statements.
Approach: They propose a system that aims to automatically summarize evidence presented in the set of randomized controlled trials most relevant to a given query.
Outcome: The proposed system retrieves trial publications matching a query specifying a combination of condition, intervention(s), and outcome(s) and ranks them according to sample size and estimated study quality.
Summarizing, Simplifying, and Synthesizing Medical Evidence using GPT-3 (with Varying Success) (2023.acl-short)

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Challenge: Large language models are capable of producing high quality summaries of general domain news articles in few- and zero-shot settings, but it is unclear whether they are similarly capable in more specialized domains such as biomedicine.
Approach: They use GPT-3 to generate single- and multi-document summaries of biomedical articles, given no supervision, using a set of annotations.
Outcome: The proposed model outperforms fully supervised models in generic news summarization, but struggles to synthesize evidence across multiple documents.
Paragraph-level Simplification of Medical Texts (2021.naacl-main)

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Challenge: Existing methods for simplification of medical texts are limited due to jargon and technical content.
Approach: They propose to automate the simplification of medical texts by penalizing decoders for producing "jargon" terms.
Outcome: The proposed method improves on existing heuristics by penalizing the decoder for producing "jargon" terms.
Appraising the Potential Uses and Harms of LLMs for Medical Systematic Reviews (2023.emnlp-main)

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Challenge: Medical systematic reviews are time-consuming and often generate inaccurate outputs . authors: a model that generates scientific-sounding outputs can be unusable at best .
Approach: They conduct interviews with systematic review experts to characterize perceived utility and risks of LLMs in medical evidence reviews.
Outcome: a new study characterizes perceived utility and risks of medical evidence reviews . experts say they can assist in the writing process by drafting summaries, distilling information . authors say they expect the model to be more accurate and more reliable .
Trialstreamer: Mapping and Browsing Medical Evidence in Real-Time (2020.acl-demos)

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Challenge: Trialstreamer extracts key pieces of information that clinicians need when appraising the literature . the highest-quality evidence to inform healthcare practice comes from randomized controlled trials .
Approach: They propose a system that extracts key pieces of information from biomedical abstracts and combines them into a database of clinical trial reports.
Outcome: The proposed system extracts descriptions of trial participants, treatments compared in each arm, and which outcomes were measured.
A Corpus with Multi-Level Annotations of Patients, Interventions and Outcomes to Support Language Processing for Medical Literature (P18-1)

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Challenge: In 2015 alone, about 100 manuscripts describing randomized controlled trials for medical interventions were published every day.
Approach: They propose a corpus of 5,000 medical articles annotated with demarcations of text spans that describe the Patient population enrolled, the Interventions studied and to what they were Compared, and the Outcomes measured.
Outcome: The proposed corpus includes 5,000 medical articles describing clinical randomized controlled trials.
Syntactic Patterns Improve Information Extraction for Medical Search (N18-2)

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Challenge: Medical professionals search the literature by specifying the type of patients, the medical intervention(s) and the outcome measure(s).
Approach: They propose to exploit the availability of structured abstracts to extract medically relevant information from syntactic patterns.
Outcome: The proposed models differ from the constituent unigrams in the extracted patterns, suggesting that they capture contextual information that is otherwise lost.
Structured Multi-Label Biomedical Text Tagging via Attentive Neural Tree Decoding (D18-1)

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Challenge: Existing methods for tagging unstructured texts with arbitrary number of terms drawn from an ontology are lacking.
Approach: They propose a model for tagging unstructured texts with an arbitrary number of terms drawn from an ontology.
Outcome: The proposed model yields state-of-the-art results on the important task of assigning MeSH terms to biomedical abstracts.

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