Challenge: Biomedical Concept Normalization (BCN) is widely used in biomedical text processing . despite numerous surface variants of biomedically-defined concepts, it remains challenging and unsolved.
Approach: They propose a framework that uses hypernyms and synonyms to facilitate BCN . they use list-wise training to make use of both hypernies and synonym entities .
Outcome: The proposed framework outperforms the state-of-the-art model on the NCBI dataset.

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Challenge: Existing methods for biomedical named entity recognition require laborious human effort.
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Challenge: Biomedical named entities are often used as key features in biomedical text mining.
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A Generate-and-Rank Framework with Semantic Type Regularization for Biomedical Concept Normalization (2020.acl-main)

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Challenge: Concept normalization is a task that maps textual mentions of concepts to concepts in an ontology . lexical and grammatical variations are pervasive in such text, posing key challenges for data interoperability and the development of natural language processing (NLP) techniques.
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Challenge: Biomedical concepts are often mentioned in medical documents under different name variations.
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Challenge: Named entity recognition (NER) and entity normalization (entity linking) are two fundamental natural language processing tasks to achieve entity normalizing.
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