Papers by Zhuoyang Jiang
CAGenMol: Condition-Aware Diffusion Language Model for Goal-Directed Molecular Generation (2026.findings-acl)
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| Challenge: | Existing methods to optimize target-directed molecular generation fail to reconcile conflicting objectives without compromising structural validity. |
| Approach: | They propose a condition-aware discrete diffusion framework that allows for conditional denoising guided by heterogeneous structural and property signals. |
| Outcome: | The proposed framework improves on structure-conditioned, property-conditioned and dual-conditioned benchmarks in binding affinity, drug-likeness, and success rate. |