Papers by Youngseung Jeon

2 papers
GraPPI: A Retrieve-Divide-Solve GraphRAG Framework for Large-scale Protein-protein Interaction Exploration (2025.findings-naacl)

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Challenge: Large Language Models and Retrieval-Augmented Generation frameworks have accelerated drug discovery, but integrating models into workflows remains challenging.
Approach: They propose a large-scale knowledge graph-based retrieve-divide-solve agent pipeline RAG framework to support large-level PPI signaling pathway exploration.
Outcome: The proposed framework is based on large-scale knowledge graphs and can be used to analyze protein-protein interactions.
RAGPPI: Retrieval-Augmented Generation Benchmark for Protein–Protein Interactions in Drug Discovery (2026.eacl-long)

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Challenge: Large Language Models and Retrieval-Augmented Generation (RAG) frameworks have supported Target ID, but no benchmark exists for identifying biological impacts of PPIs.
Approach: They propose to build a factual question-answer benchmark of 4,420 question-announced pairs that focus on the potential biological impacts of PPIs.
Outcome: The proposed benchmark is based on 4,420 question-answer pairs with expert-driven data annotation.

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