Papers by Maxime Delmas
Accelerating Antibiotic Discovery with Large Language Models and Knowledge Graphs (2025.acl-industry)
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| Challenge: | Antimicrobial resistance (AMR) is one of the top ten global public health threats . pharmaceutical industries face high costs (over $1 billion), long timelines, and a high failure rate . |
| Approach: | They propose an LLM-based pipeline that acts as an alert system, detecting prior evidence of antibiotic activity to prevent costly rediscoveries. |
| Outcome: | The proposed system integrates literature on organisms and chemicals into a Knowledge Graph (KG), ensuring taxonomic resolution, synonym handling, and multi-level evidence classification. |