Challenge: Existing supervised systems are highly data-driven and require a lot of effort to label data for a new domain.
Approach: They propose to transfer knowledge from one or more related source domains to another domain to improve relation classification.
Outcome: The proposed model outperforms neural-network based models on biomedical datasets and with contextualized embeddings on 3 biomedically-relevant datasets.

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Entity Enhancement for Implicit Discourse Relation Classification in the Biomedical Domain (2021.acl-short)

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Challenge: Discourse relation classification is a challenging task when the text domain is different from the standard Penn Discourse Treebank (PDTB) training corpus domain.
Approach: They propose to use the Biomedical Discourse Relation Bank to improve discourse relational argument representation by linking explicit instances of similar relations with a voting pipeline.
Outcome: The proposed model outperforms the pre-trained BioBERT model by 2% points.
How to Encode Domain Information in Relation Classification (2024.lrec-main)

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Challenge: Existing deep learning models require a lot of training data to obtain high performance.
Approach: They propose a multi-domain training setup for Relation Classification (RC) they compare different ways to enrich input instances with domain information .
Outcome: The proposed model improves > 2 Macro-F1 against the baseline setup.
Named Entity Recognition Under Domain Shift via Metric Learning for Life Sciences (2024.naacl-long)

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Challenge: Existing models for named entity recognition fail in scientific domains such as biomedicine and chemistry.
Approach: They propose a model to transfer knowledge from the biomedical domain to the target domain . they use pseudo labeling and contrastive learning to enhance discrimination .
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MedDistant19: Towards an Accurate Benchmark for Broad-Coverage Biomedical Relation Extraction (2022.coling-1)

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Challenge: Relation extraction in the biomedical domain is challenging due to the lack of labeled data and high annotation costs.
Approach: They propose to use distant supervision to pair knowledge graph relationships with raw texts to tackle the scarcity of annotated data and to validate their results.
Outcome: The proposed benchmarks are more accurate and consistent with existing benchmarks and show that there is no train-test leakage.
Syntax-aware Multi-task Graph Convolutional Networks for Biomedical Relation Extraction (D19-62)

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Challenge: 80% of the data sets for relation extraction tasks are negative instances, resulting in a lack of syntactic information between two entity mentions.
Approach: They propose a graph convolutional networks model that incorporates dependency parsing and contextualized embedding to capture comprehensive contextual information.
Outcome: The proposed model achieves state-of-the-art F-score on the 2013 drug-drug interaction extraction task.
Biomedical relation extraction with pre-trained language representations and minimal task-specific architecture (D19-57)

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Challenge: Using a pre-trained BERT-Base model, we learn domain-specific language representations using biomedical text.
Approach: They propose a system that extends BERT, a state-of-the-art language model, which learns contextual language representations from a large unlabelled corpus.
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Leveraging Dependency Forest for Neural Medical Relation Extraction (D19-1)

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Challenge: Existing methods for medical relation extraction use dependency syntax as a source of features.
Approach: They propose a method to extract relational information from medical literature by using dependency forests.
Outcome: The proposed method outperforms the standard tree-based methods in the medical domain.
Bio-RFX: Refining Biomedical Extraction via Advanced Relation Classification and Structural Constraints (2024.emnlp-main)

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Challenge: Existing methods for extracting structured data from unstructured texts neglect unique features of the biomedical literature, such as ambiguous entities and nested proper nouns.
Approach: They propose a model that leverages sentence-level relation classification before entity extraction to tackle entity ambiguity.
Outcome: The proposed model outperforms baselines in both NER and RE tasks and has competitive performance compared to the state-of-the-art fine-tuned baselines for RE.
BioMegatron: Larger Biomedical Domain Language Model (2020.emnlp-main)

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Challenge: Existing studies on domain language models do not study the factors affecting performance on domain languages.
Approach: They empirically evaluate factors that can affect performance on domain language applications . sub-word vocabulary set, model size, pre-training corpus, and domain transfer are important .
Outcome: The results show language models trained on biomedical text perform better on biomedicine benchmarks than those trained on general domain text corpora.
Incorporating medical knowledge in BERT for clinical relation extraction (2021.emnlp-main)

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Challenge: Pre-trained language models (PLMs) are used for diverse NLP tasks such as Information Extraction, Sentiment Analysis and Question/Answering.
Approach: They propose to add medical knowledge to pre-trained language models to facilitate clinical relation extraction using a large text corpus.
Outcome: The proposed model outperforms the state-of-the-art systems on the benchmark i2b2/VA 2010 clinical relation extraction dataset.

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