Challenge: Existing studies on relation extraction focus on document-level training without sharing raw medical texts.
Approach: They propose a federated framework for relation extraction that enables collaborative training without sharing raw medical texts.
Outcome: The proposed framework extends document-level relation extraction to a federated environment.

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Distantly Supervised Relation Extraction in Federated Settings (2021.findings-emnlp)

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Challenge: Existing methods to label training datasets using distant supervision are expensive and cannot cover all walks of life.
Approach: They propose a federated denoising framework to suppress label noise in federation . they propose to use a multiple instance learning based denoisation method to select reliable sentences .
Outcome: The proposed method can select reliable sentences via cross-platform collaboration.
FedED: Federated Learning via Ensemble Distillation for Medical Relation Extraction (2020.emnlp-main)

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Challenge: Existing relation extraction methods require centralizing training data from different medical platforms while holding the privacy-sensitive data puts patients' privacy at risk.
Approach: They propose a federated relation extraction model that trains a central model without sharing or exchange of private local data.
Outcome: The proposed model trains a central model without uploading local parameters, and it performs well on three publicly available datasets.
Modular Self-Supervision for Document-Level Relation Extraction (2021.emnlp-main)

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Challenge: Prior work on information extraction tends to focus on binary relations within sentences . practical applications often require extracting complex relations across large text spans .
Approach: They propose to decompose document-level relation extraction into relation detection and argument resolution, taking inspiration from Davidsonian semantics.
Outcome: The proposed method outperforms state-of-the-art methods in biomedical machine reading for precision oncology by 20 absolute F1 points.
Global-to-Local Neural Networks for Document-Level Relation Extraction (2020.emnlp-main)

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Challenge: Relation extraction (RE) aims to identify the semantic relations between named entities in text.
Approach: They propose a novel relation extraction model that encodes document information in terms of entity global and local representations and context relation representations.
Outcome: The proposed model achieves superior performance on two public datasets for document-level RE.
Enhanced Reasoning for Biomedical Document-Level Relation Extraction via a Novel Cascade Language Model Framework (2026.acl-long)

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Challenge: Pre-trained language models (PLMs) are the leading paradigm in document-level relation extraction.
Approach: They propose a cascade framework that leverages the complementary strengths of PLMs and LLMs through a detect-then-rethink paradigm.
Outcome: The proposed framework improves on BioRED and CDR datasets and improves existing models.
HiCLRE: A Hierarchical Contrastive Learning Framework for Distantly Supervised Relation Extraction (2022.findings-acl)

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Challenge: Existing approaches of distantly supervised relation extraction (DSRE) focus on sentence-level or bag-level de-noising, neglecting the explicit interaction with cross levels.
Approach: They propose a hierarchical contrastive learning framework for distantly supervised relation extraction to reduce noisy sentences.
Outcome: The proposed framework outperforms baselines in various mainstream DSRE datasets.
Global Context-enhanced Graph Convolutional Networks for Document-level Relation Extraction (2020.coling-main)

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Challenge: Existing approaches to document-level relation extraction are difficult to establish direct connections between distant entity pairs.
Approach: They propose a global context-enhanced Graph Convolutional Network model which captures rich global context information of entities in a document.
Outcome: The proposed model captures rich global context information of entities in a document.
Towards Integration of Discriminability and Robustness for Document-Level Relation Extraction (2023.eacl-main)

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Challenge: Document-level relation extraction (DocRE) predicts relations for entity pairs relying on context-dependent reasoning . a large number of annotation errors can make it difficult to distinguish large semantically close relations .
Approach: They propose a loss function to improve discriminability and robustness for DocRE . they also propose supervised contrastive learning and negative label sampling strategy .
Outcome: The proposed method achieves state-of-the-art results on the DocRED dataset and its recently cleaned version.
TTM-RE: Memory-Augmented Document-Level Relation Extraction (2024.acl-long)

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Challenge: Existing methods for document-level relation extraction are ineffective in exploiting the full potential of large amounts of training data with varied noise levels.
Approach: They propose a novel approach that integrates a trainable memory module with a noisy-robust loss function that accounts for the positive-unlabeled setting to unlock the full potential of large-scale noisy training data.
Outcome: The proposed model outperforms existing methods on a ReDocRED benchmark dataset with an absolute F1 score improvement of over 3%.
Bio-RFX: Refining Biomedical Extraction via Advanced Relation Classification and Structural Constraints (2024.emnlp-main)

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Challenge: Existing methods for extracting structured data from unstructured texts neglect unique features of the biomedical literature, such as ambiguous entities and nested proper nouns.
Approach: They propose a model that leverages sentence-level relation classification before entity extraction to tackle entity ambiguity.
Outcome: The proposed model outperforms baselines in both NER and RE tasks and has competitive performance compared to the state-of-the-art fine-tuned baselines for RE.

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