Challenge: Large language models have a tendency to make confidently wrong predictions, highlighting the need for uncertainty quantification (UQ) . previous studies focused on aleatoric uncertainty, but the full spectrum of uncertainties, including epistemic, remains inadequately explored.
Approach: They propose a method to quantify uncertainty in large language models (LLMs) they use a set of perturbations and an aggregation module to generalize the method.
Outcome: The proposed method improves model uncertainty calibration and reduces expected calibration error by 50% on average.

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Challenge: Existing research on Uncertainty Quantification (UQ) predominantly targets short text generation, however, real-world applications often necessitate much longer responses.
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Challenge: Large language models (LLMs) produce hallucinations, which undermine user trust and reliability.
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Challenge: Uncertainty quantification (UQ) provides measures of uncertainty, such as an estimate of the confidence in an LLM’s generated output.
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Challenge: Existing methods for uncertainty quantification fail to capture multifaceted nature of natural language generation.
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IUQ: Interrogative Uncertainty Quantification for Long-Form Large Language Model Generation (2026.acl-long)

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Challenge: Recent approaches to quantify uncertainty in LLMs produce short or constrained answer sets, but many real-world applications require long-form and free-form text generation.
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Challenge: Uncertainty quantification (UQ) is a prominent approach for eliciting truthful answers from large language models (LLMs).
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Challenge: ArgLLMs are an explainable LLM framework for decision-making based on computational argumentation in which uncertainty quantification plays a critical role.
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Uncertainty Quantification in LLM Agents: Foundations, Emerging Challenges, and Opportunities (2026.acl-long)

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Challenge: Uncertainty quantification (UQ) for large language models is a key building block for daily applications.
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Shifting Attention to Relevance: Towards the Predictive Uncertainty Quantification of Free-Form Large Language Models (2024.acl-long)

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Challenge: Large Language Models (LLMs) show promising results in language generation but often “hallucinate”, making their outputs less reliable.
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Uncertainty Quantification for In-Context Learning of Large Language Models (2024.naacl-long)

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Challenge: Existing studies on in-context learning have focused on quantifying the uncertainty associated with the model's response, but they neglect the complexity of the LLM and the uniqueness of in-constitut learning.
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