Challenge: Diagnostic coding is the task of assigning diagnosis codes defined by the ICD (International Classification of Diseases) standard to patient visits based on clinical notes.
Approach: They propose to use an ICD coding framework to train and benchmark models . they correct errors in preprocessing and provide an interactive demo to analyze the models based on custom inputs.
Outcome: The framework corrects errors in preprocessing and provides key models and weights trained on correctly preprocessed datasets.

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A Neural Architecture for Automated ICD Coding (P18-1)

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Challenge: Medical coding is time-consuming, expensive, and error prone.
Approach: They propose to use diagnosis descriptions (DDs) of a patient as inputs to select the most relevant ICD codes.
Outcome: The proposed algorithms perform on a clinical dataset with 59K patient visits.
A Two-Stage Decoder for Efficient ICD Coding (2023.findings-acl)

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Challenge: Recent automated ICD coding efforts improve performance by encoding medical notes and codes with additional data and knowledge bases.
Approach: They propose a two-stage decoding mechanism to predict ICD codes using hierarchical properties of the codes to split the prediction into two steps: at first, predict the parent code and then predict the child code based on the previous prediction.
Outcome: Experiments on the public MIMIC-III data show that the proposed model performs well in single-model settings without external data or knowledge.
A General Knowledge Injection Framework for ICD Coding (2025.findings-acl)

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Challenge: Existing methods to improve ICD coding focus on a single type of knowledge and design specialized modules that are complex and incompatible with each other.
Approach: They propose a general knowledge injection framework that integrates three key types of knowledge without specialized design of additional modules.
Outcome: The proposed framework outperforms baseline models and is comparable to models relying on extra human annotations.
MedCodER: A Generative AI Assistant for Medical Coding (2025.naacl-industry)

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Challenge: Medical coding is time-consuming and error-prone due to large label space, lengthy text inputs, and the absence of supporting evidence annotations.
Approach: They propose a Generative AI framework for automatic medical coding that leverages extraction, retrieval, and re-ranking techniques as core components.
Outcome: The proposed framework outperforms existing methods on the International Classification of Diseases (ICD) code prediction scale.
Automatic ICD Coding Exploiting Discourse Structure and Reconciled Code Embeddings (2022.coling-1)

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Challenge: Existing studies did not exploit the discourse structure of clinical notes, which provides rich contextual information for code assignment.
Approach: They propose to leverage section type classification and section type embeddings to exploit the discourse structure of clinical notes to generate rich contextual information for code assignment.
Outcome: The proposed model outperforms state-of-the-art models on a MIMIC dataset by a large margin.
CoRelation: Boosting Automatic ICD Coding through Contextualized Code Relation Learning (2024.lrec-main)

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Challenge: Existing methods for boosting ICD coding performance lack a model for complex code relations . current methods overlook the importance of context in clinical notes .
Approach: They propose a contextualized and flexible framework to enhance learning of ICD code relations . they use clinical notes to model all possible code relations using a dependent learning paradigm .
Outcome: The proposed approach improves on six public ICD coding datasets compared to state-of-the-art models.
Code Like Humans: A Multi-Agent Solution for Medical Coding (2025.findings-emnlp)

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Challenge: In medical coding, experts map unstructured clinical notes to alphanumeric codes for diagnoses and procedures.
Approach: They introduce ‘Code Like Humans’: a new agentic framework for medical coding with large language models that implements official coding guidelines for human experts.
Outcome: The proposed framework implements official coding guidelines for human experts and can support the full ICD-10 coding system (+70K labels).
Travel on the ICD Tree: Benchmarking Agentic Reasoning for ICD Coding from Chinese Electronic Medical Records (2026.findings-acl)

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Challenge: Accurate International Classification of Diseases (ICD) coding is crucial for hospital management and healthcare data governance.
Approach: They propose a framework to evaluate ICD coding based on complete EMRs . they use a dataset of 560 real clinical records covering 434 common diseases .
Outcome: The proposed framework explores the capability boundaries of large language models under different paradigms.
Less is More: Explainable and Efficient ICD Code Prediction with Clinical Entities (2025.acl-long)

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Challenge: Clinical coding is labor-intensive and prone to delays, leading to global backlogs.
Approach: They propose an approach that combines Named Entity Recognition (NER) and Assertion Classification (AC) to filter for clinically important content before supervised code prediction.
Outcome: The proposed approach reduces training time by over half on a standard evaluation dataset compared to current methods . it uses Named Entity Recognition (NER) and Assertion Classification (AC) to filter for clinically important content before supervised code prediction.
Auxiliary Knowledge-Induced Learning for Automatic Multi-Label Medical Document Classification (2024.lrec-main)

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Challenge: Existing methods for ICD indexing use machine learning to assign subset of codes to medical records . experimental results show proposed method achieves state-of-the-art performance on a number of measures.
Approach: They propose a method that uses a deep dilated residual convolution encoder to learn document representations across different lengths of the texts.
Outcome: The proposed method achieves state-of-the-art performance on a number of measures.

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